Lineage-specific intolerance to oncogenic drivers restricts histological transformation
Science | February 8, 2024

Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation
Nature Cancer | January 29, 2024

Non-cell-autonomous cancer progression from chromosomal instability
Nature | August 23, 2023

Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation
Cell Systems | April 19, 2023

Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression   Nature Communications | October 20, 2022

Loss of polycomb repressive complex 1 activity and chromosomal instability drive uveal melanoma progression
Nature Communications | September 13, 2021

Cancer metastasis as a non-healing wound
British Journal of Cancer | March 17, 2021

The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution
Cell | April 16, 2020

Regenerative lineages and immune-mediated pruning in lung cancer metastasis
Nature Medicine | February 10, 2020

Adult Human Glioblastomas Harbor Radial Glia-like Cells.
Stem Cell Reports | January 15, 2020

Regenerative origin of L1CAM+ metastasis initiating cells
Nature Cancer | January 13, 2020

Urothelial organoids originating from CD49fhigh mouse stem cells display Notch-dependent differentiation capacity
Nature Communications | September 27, 2019

A Markov chain for numerical chromosomal instability in clonally expanding populations
PLOS Computational Biology | September 11, 2018

Chromosomal instability drives metastasis through a cytosolic DNA response
Nature | January 25, 2018

Predicting therapeutic nanoparticle efficacy using a companion MR imaging nanoparticle
Science Translational Medicine | November 18, 2015

Dynamics of tumor heterogeneity derived from clonal karyotypic evolution
Cell Reports | August 4, 2015

Numerical chromosomal instability increases susceptibility to radiation treatment
Nature Communications | January 21, 2015

Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin
Science Translational Medicine | November 5, 2014

In vivo imaging of multidrug resistance using a third generation MDR1 inhibitor
Bioconjugate Chem | June 18, 2014

Photoactivatable Drug-Caged Fluorophore Conjugate Allows Direct Quantification of Intracellular Drug Transport
Chemical Communications | October 18, 2013

Spectral discrimination of breast pathologies in situ using spatial frequency domain imaging
Breast Cancer Research | August 15, 2013

Direct identification of breast cancer pathologies using blind separation of label-free localized reflectance measurements
Biomedical Optics Express | June 12, 2013

System analysis of spatial frequency domain imaging for quantitative mapping of surgically resected breast tissues
Journal of Biomedical Optics | March 18, 2013

Scanning in situ Spectroscopy platform for imaging surgical breast tissue specimens
Optics Express | January 28, 2013

Scatter spectroscopic imaging distinguishes breast pathologies in tissues relevant to surgical margin assessment
Clinical Cancer Research | November 15, 2012

Dark-Field In Situ Scanning Spectroscopy Platform for Broadband Imaging of Resected Tissue
Optics Letters | May 15, 2011

Automated classification of breast pathology using local measures of broadband reflectance
Journal of Biomedical Optics | November 15, 2010

Measurement of pressure displacement kinetics of hemoglobin in normal breast tissue with near-infrared spectral imaging
Applied Optics | April 1, 2009