Transforming lung cancer types
Lung cancer cells can escape targeted therapy by switching oncogenic drivers and cell identity. …
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Publications
Non-cell-autonomous cancer progression from chromosomal instability
Chromosomal instability (CIN) is a driver of cancer metastasis, yet the extent to which this effect depends on the immune system remains…
Loss of polycomb repressive complex 1 activity and chromosomal instability drive uveal melanoma progression
NATURE COMMUNICATIONS – Chromosomal instability (CIN) and epigenetic alterations have been implicated in tumor progression and metastasis; yet how these…
Regenerative lineages and immune-mediated pruning in lung cancer metastasis
NATURE MEDICINE – Developmental processes underlying normal tissue regeneration have been implicated in cancer, but the degree of their enactment…