L1CAM links regeneration to metastasis
NATURE CANCER – Metastasis competence can be acquired early in tumorigenesis, although its underlying molecular intricacies remain unclear. A recent…
© 2020 Laughney Lab. All Rights Reserved
News
Dr. Ashley Laughney Applies Problem-Solving Skills to Lung Cancer Research
Ashley Laughney, Ph.D., a CSBC junior investigator at Memorial Sloan Kettering Cancer Center, trained in engineering, which she describes as…
Chromosomal Instability Drives Cancer Metastasis
Aneuploidy—the presence of abnormal numbers of chromosomes in a cell—is associated with cancer metastasis, but scientists have struggled to connect…
Chromosomal Instability Drives Metastasis Independent of Aneuploidy
Chromosomal instability (CIN), which results from ongoing chromosome segregation errors in mitosis, is associated with metastasis. However, it is not…
Deadly role of chromosomal instability in metastasis
Chromosomal instability produces cytosolic micronuclei that rupture and activate a viral response pathway, driving metastasis. Read Article >
How Metastasis Is Driven By Chromosomal Instability
Metastasis, the migration of cancer cells from a primary tumor to form distant tumors in the body, can be triggered…
How cancer metastasis happens: Researchers reveal a key mechanism
Cancer metastasis, the migration of cells from a primary tumor to form distant tumors in the body, can be triggered…
Chromosomal instability can trigger metastasis via STING activity
A paper published in Nature brings into question the safety and efficacy of activating the transmembrane protein 173 (STING; TMEM173)…
Can STING agonists promote cancer metastasis?
That’s the intriguing question posed by research published recently in the journal Nature by Dr Samuel Bakhoum and colleagues, who…
Interdisciplinary postdocs ‘bridging science fiction with reality’ will share $5M in career grants.
Burroughs Wellcome Fund Recognizes Ten Scientists Combining Biology with the Physical Sciences and Engineering Towards Medical Breakthroughs. RESEARCH TRIANGLE PARK,…