Transforming lung cancer types
Lung cancer cells can escape targeted therapy by switching oncogenic drivers and cell identity. …
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News
Non-cell-autonomous cancer progression from chromosomal instability
Chromosomal instability (CIN) is a driver of cancer metastasis, yet the extent to which this effect depends on the immune system remains…
Cancer Rewires STING Pathway to Metastasize
Researchers at Memorial Sloan Kettering Cancer Center (MSK) and Weill Cornell Medicine discovered a new relationship between cancer cells and…
Doctors identify an eye cancer culprit
Researchers have identified a molecular mechanism that drives the progression of uveal melanoma (UM), an often lethal eye cancer in…
Loss of polycomb repressive complex 1 activity and chromosomal instability drive uveal melanoma progression
Chromosomal instability (CIN) and epigenetic alterations have been implicated in tumor progression and metastasis; yet how these two hallmarks of…
Uveal Melanoma Discovery Points to New Treatment Possibilities
A team co-led by scientists at Weill Cornell Medicine has revealed in detail how the most common primary eye cancer…
The emerging role of cancer cell plasticity and cell-cycle quiescence in immune escape
Molecular programs that control the function and the phenotype of stem cells are also active in cancer and confer properties…
Immunoediting of cancer metastasis by NK cells
Natural killer (NK) cells serve a critical role in the control of metastasis. NK cells are now shown to preferentially…
Shape-Shifting Stem Cells Are Key to Cancer Metastasis and Immune Evasion
Just as people tend to become stuck in their ways as they grow older so too do cells. Neurons in…
What Does Cancer Metastasis Have to Do with Wound Healing? More than You Might Think
Metastasis — the spreading of cancer to other regions in the body — is responsible for 90% of cancer deaths.…