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Chromosomal instability can trigger metastasis via STING activity

  • Papers
  • 1 min read

A paper published in Nature brings into question the safety and efficacy of activating the transmembrane protein 173 (STING; TMEM173) pathway — which triggers immune responses in the presence of cytosolic DNA — in cancers with chromosomal instability.

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We are affiliated with the Institute for Computational Biomedicine, the Department of Physiology, Biophysics and Systems Biology, the Tri-Institutional PhD Program in Computational Biology and Medicine, and the Meyer Cancer Center at Weill Cornell Medicine.
Principle Investigator:
Ashley Laughney, PhD

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Ashley.laughney@gmail.com

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