Molecular programs that control the function and the phenotype of stem cells are also active in cancer and confer properties…
Natural killer (NK) cells serve a critical role in the control of metastasis. NK cells are now shown to preferentially…
Just as people tend to become stuck in their ways as they grow older so too do cells. Neurons in…
NATURE MEDICINE – Developmental processes underlying normal tissue regeneration have been implicated in cancer, but the degree of their enactment…
NATURE – Chromosomal instability is a hallmark of cancer that results from ongoing errors in chromosome segregation during mitosis. Although…
Metastasis — the spreading of cancer to other regions in the body — is responsible for 90% of cancer deaths.…
NATURE CANCER – Metastasis competence can be acquired early in tumorigenesis, although its underlying molecular intricacies remain unclear. A recent…
NATURE CANCER – Metastasis-initiating cells with stem-like properties drive cancer lethality, yet their origins and relationship to primary-tumor-initiating stem cells…
CELL REPORTS – Numerical chromosomal instability is a ubiquitous feature of human neoplasms. Due to experimental limitations, fundamental characteristics of…
Radial glia (RG) cells are the first neural stem cells to appear during embryonic development. Adult human glioblastomas harbor a…
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